0- SWITCH OFF 24V on GPIO 1- CONNECT THE USB Blaster II on J9 (10-pins header) FPGA-PROG connector 2- OPEN QUARTUS II PRIME PROGRAMMER (see below for download) 3- BUTTON 'Hardware SETUP...' : select 'USB-BLASTER' in list 4- SELECT Mode : 'ACTIVE SERIAL PROGRAMMING' 5- BUTTON 'Add File...' : select the .pof file in the FPGA version directory 6- CHECK boxes : 'Program/Configure' + 'Verify' + 'BlankCheck' 7- SWITCH ON 24V on GPIO 8- BUTTON 'START' 9- SWITCH OFF 24V on GPIO 10- DISCONNECT THE USB Blaster II on J9 (10-pins header) FPGA-PROG connector 11- OPEN UNIGE GUI AND VERIFY that version corresponds to the FPGA version you've downloaded Quartus Prime Programmer Download for v18.1: http://fpgasoftware.intel.com/18.1/?edition=standard&platform=windows&download_manager=dlm3&product=qprogrammer#tabs-4